The liver is undoubtedly one of the most important
The liver is undoubtedly one of the most important organs in our body as it is responsible for a major share of our body's metabolism. Furthermore, our liver also helps in refining toxins out of our body. However, constant damage to the liver can lead to cirrhosis, and in advanced stages, patients may need a liver transplant. The following discussion dives into details regarding liver cirrhosis and the scenarios in which you may need a transplant. Liver Cirrhosis Cirrhosis is the end result of various types of liver diseases that generally involve abnormal functioning and changes in the structure of the liver. The liver diseases leading up to cirrhosis tend to damage and kill the liver cells. The subsequent inflammation and repair of damaged liver cells lead to the formation of scar tissue. In addition, healthy liver cells continue regenerating for replacing the dead liver cells. As a result, the newly-formed liver cells group together and form regenerative nodules in the scar tissue. When the volume of scar tissue increases, the liver gradually loses abilities for performing the normal functions. Causes for Liver Cirrhosis Being obese or overweight, consumption of too much alcohol and instances of viral hepatitis are some of the risk factors for cirrhosis of liver. However, the causes for liver damage leading to liver cirrhosis are as follows: Increased pressure on the portal vein of the liver Hepatitis that causes inflammation in the liver Alcoholism resulting in liver damage Non-alcoholic fatty liver disease that results in a fat buildup in liver cells Primary biliary cirrhosis that occurs due to blockage and inflammation in the bile ducts Inherited diseases such as cystic fibrosis, hemochromatosis, Wilson's disease and autoimmune diseases such as lupus and HIV.
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